BDBM17606 2-[(4-fluorobenzene)sulfonamido]-8-methyl-5,6-dihydronaphthalene-1-carboxylic acid::sulfonamide compound, 12

SMILES: CC1=CCCc2ccc(NS(=O)(=O)c3ccc(F)cc3)c(C(O)=O)c12

InChI Key: InChIKey=OCRFJQHVDVDJIO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17606 (2-[(4-fluorobenzene)sulfonamido]-8-methyl-5,6-dihy...) Show SMILES CC1=CCCc2ccc(NS(=O)(=O)c3ccc(F)cc3)c(C(O)=O)c12 |t:1| Show InChI InChI=1S/C18H16FNO4S/c1-11-3-2-4-12-5-10-15(17(16(11)12)18(21)22)20-25(23,24)14-8-6-13(19)7-9-14/h3,5-10,20H,2,4H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
					More data for this Ligand-Target Pair