BDBM176083 US10047103, 116::US9688695, 116

SMILES: COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccno3)cc(OC)cc2o1

InChI Key: InChIKey=HEYYTJUHMHNLMD-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 4 (PAR4) (Homo sapiens (Human))	BDBM176083 (US10047103, 116 | US9688695, 116) Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccno3)cc(OC)cc2o1 Show InChI InChI=1S/C21H15N5O5S2/c1-27-12-5-16(29-9-11-10-32-19(23-11)15-3-4-22-31-15)13-7-18(30-17(13)6-12)14-8-26-20(24-14)33-21(25-26)28-2/h3-8,10H,9H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.320	n/a	n/a	n/a	25
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...				US Patent US9688695 (2017) BindingDB Entry DOI: 10.7270/Q28K777N
					More data for this Ligand-Target Pair
Proteinase-activated receptor 4 (PAR4) (Homo sapiens (Human))	BDBM176083 (US10047103, 116 | US9688695, 116) Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccno3)cc(OC)cc2o1 Show InChI InChI=1S/C21H15N5O5S2/c1-27-12-5-16(29-9-11-10-32-19(23-11)15-3-4-22-31-15)13-7-18(30-17(13)6-12)14-8-26-20(24-14)33-21(25-26)28-2/h3-8,10H,9H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.320	n/a	n/a	n/a	25
Bristol-Myers Squibb Company; Universite de Montreal US Patent					Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...				US Patent US10047103 (2018) BindingDB Entry DOI: 10.7270/Q2QF8VWN
					More data for this Ligand-Target Pair