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SMILES: COc1cc(OCc2csc(n2)C2(F)CCOCC2)c2cc(oc2c1)-c1cn2nc(C)ccc2n1

InChI Key: InChIKey=SXAHCZLVEBNFID-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 4 (Homo sapiens (Human))	BDBM176179 (US10047103, 212 | US9688695, 212) Show SMILES COc1cc(OCc2csc(n2)C2(F)CCOCC2)c2cc(oc2c1)-c1cn2nc(C)ccc2n1 Show InChI InChI=1S/C25H23FN4O4S/c1-15-3-4-23-28-19(12-30(23)29-15)22-11-18-20(9-17(31-2)10-21(18)34-22)33-13-16-14-35-24(27-16)25(26)5-7-32-8-6-25/h3-4,9-12,14H,5-8,13H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.290	n/a	n/a	n/a	25
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...				US Patent US9688695 (2017) BindingDB Entry DOI: 10.7270/Q28K777N
					More data for this Ligand-Target Pair
Proteinase-activated receptor 4 (Homo sapiens (Human))	BDBM176179 (US10047103, 212 | US9688695, 212) Show SMILES COc1cc(OCc2csc(n2)C2(F)CCOCC2)c2cc(oc2c1)-c1cn2nc(C)ccc2n1 Show InChI InChI=1S/C25H23FN4O4S/c1-15-3-4-23-28-19(12-30(23)29-15)22-11-18-20(9-17(31-2)10-21(18)34-22)33-13-16-14-35-24(27-16)25(26)5-7-32-8-6-25/h3-4,9-12,14H,5-8,13H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.290	n/a	n/a	n/a	25
Bristol-Myers Squibb Company; Universite de Montreal US Patent					Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...				US Patent US10047103 (2018) BindingDB Entry DOI: 10.7270/Q2QF8VWN
					More data for this Ligand-Target Pair