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BDBM176604 US9115121, 46

SMILES: COc1nc(NCCc2ccc(OC(F)F)cc2)nc(n1)-c1ccc(Cl)c(c1)C(C)(C)O

InChI Key: InChIKey=ZFVLQYHAZBKKAJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176604   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM176604
PNG
(US9115121, 46)
Show SMILES COc1nc(NCCc2ccc(OC(F)F)cc2)nc(n1)-c1ccc(Cl)c(c1)C(C)(C)O
Show InChI InChI=1S/C22H23ClF2N4O3/c1-22(2,30)16-12-14(6-9-17(16)23)18-27-20(29-21(28-18)31-3)26-11-10-13-4-7-15(8-5-13)32-19(24)25/h4-9,12,19,30H,10-11H2,1-3H3,(H,26,27,28,29)
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.20n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
Affinity binding tests were performed according to the experimental conditions described by M. Rinaldi-Carmona in J. Pharmacol. Exp. Therap. 1998, 28...


Citation and Details
More data for this
Ligand-Target Pair