BDBM176749 US9675612, 4 2-Benzyl-N-(6-methoxy-1H-indazol-5-yl)[1,3]thiazolo[5,4-d]pyrimidin-7-amine

SMILES: COc1cc2[nH]ncc2cc1Nc1ncnc2sc(Cc3ccccc3)nc12

InChI Key: InChIKey=YVRHMSDAWKCNBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176749 (US9675612, 4 2-Benzyl-N-(6-methoxy-1H-indazol-5-yl...) Show SMILES COc1cc2[nH]ncc2cc1Nc1ncnc2sc(Cc3ccccc3)nc12 Show InChI InChI=1S/C20H16N6OS/c1-27-16-9-14-13(10-23-26-14)8-15(16)24-19-18-20(22-11-21-19)28-17(25-18)7-12-5-3-2-4-6-12/h2-6,8-11H,7H2,1H3,(H,23,26)(H,21,22,24)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.5	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair