BDBM176761 US9675612, 8 2-Cyclohexyl-N-(1H-indazol-5-yl)[1,3]thiazolo[5,4-d]pyrimidin-7-amine

SMILES: C1CCC(CC1)c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1

InChI Key: InChIKey=ZCZORJWUOGQOPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176761 (US9675612, 8 2-Cyclohexyl-N-(1H-indazol-5-yl)[1,3]...) Show SMILES C1CCC(CC1)c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1 Show InChI InChI=1S/C18H18N6S/c1-2-4-11(5-3-1)17-23-15-16(19-10-20-18(15)25-17)22-13-6-7-14-12(8-13)9-21-24-14/h6-11H,1-5H2,(H,21,24)(H,19,20,22)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	7.5	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair