BDBM176767 US9675612, 11 2-Benzyl-N-(1H-indazol-5-yl)[1,3]thiazolo[5,4-d]pyrimidin-7-amine

SMILES: C(c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1)c1ccccc1

InChI Key: InChIKey=YFLGGBCOCXFXSQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176767 (US9675612, 11 2-Benzyl-N-(1H-indazol-5-yl)[1,3]thi...) Show SMILES C(c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1)c1ccccc1 Show InChI InChI=1S/C19H14N6S/c1-2-4-12(5-3-1)8-16-24-17-18(20-11-21-19(17)26-16)23-14-6-7-15-13(9-14)10-22-25-15/h1-7,9-11H,8H2,(H,22,25)(H,20,21,23)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair