BDBM176772 US9675612, 15 N-(6-Methoxy-1H-indazol-5-yl)[1,3]thiazolo[5,4-d]pyrimidin-7-amine

SMILES: COc1cc2[nH]ncc2cc1Nc1ncnc2scnc12

InChI Key: InChIKey=SYJNMKWDALZJGZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176772 (US9675612, 15 N-(6-Methoxy-1H-indazol-5-yl)[1,3]th...) Show SMILES COc1cc2[nH]ncc2cc1Nc1ncnc2scnc12 Show InChI InChI=1S/C13H10N6OS/c1-20-10-3-8-7(4-17-19-8)2-9(10)18-12-11-13(15-5-14-12)21-6-16-11/h2-6H,1H3,(H,17,19)(H,14,15,18)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	7.5	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair