BDBM176796 US9675612, 34 {7-[(6-Ethoxy-1H-indazol-5-yl)amino][1,3]thiazolo[5,4-d]pyrimidin-2-yl}(piperidin-1-yl)methanone

SMILES: CCOc1cc2[nH]ncc2cc1Nc1ncnc2sc(nc12)C(=O)N1CCCCC1

InChI Key: InChIKey=XXQQLBYIKZQGJQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176796 (US9675612, 34 {7-[(6-Ethoxy-1H-indazol-5-yl)amino]...) Show SMILES CCOc1cc2[nH]ncc2cc1Nc1ncnc2sc(nc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H21N7O2S/c1-2-29-15-9-13-12(10-23-26-13)8-14(15)24-17-16-18(22-11-21-17)30-19(25-16)20(28)27-6-4-3-5-7-27/h8-11H,2-7H2,1H3,(H,23,26)(H,21,22,24)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	7.5	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair