BDBM17748 2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline::4-(6,7-dimethylquinoxalin-2-yl)benzene-1,2-diol::AG1433::SU 1433

SMILES: Cc1cc2ncc(nc2cc1C)-c1ccc(O)c(O)c1

InChI Key: InChIKey=SMKFYHOKXJUJOT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (aa 538-972) ()	BDBM17748 (2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...) Show SMILES Cc1cc2ncc(nc2cc1C)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N2O2/c1-9-5-12-13(6-10(9)2)18-14(8-17-12)11-3-4-15(19)16(20)7-11/h3-8,19-20H,1-2H3	PDB GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	22
Johnson & Johnson Pharmaceutical					Assay Description The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...				J Biol Chem 282: 4085-93 (2007) Article DOI: 10.1074/jbc.M608182200 BindingDB Entry DOI: 10.7270/Q2NK3C8N
					More data for this Ligand-Target Pair
6His.FMS.538-922(FGFR) (Human Sapiens (Human))	BDBM17748 (2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...) Show SMILES Cc1cc2ncc(nc2cc1C)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N2O2/c1-9-5-12-13(6-10(9)2)18-14(8-17-12)11-3-4-15(19)16(20)7-11/h3-8,19-20H,1-2H3	PDB GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	7.5	22
Johnson & Johnson Pharmaceutical					Assay Description The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...				J Biol Chem 282: 4085-93 (2007) Article DOI: 10.1074/jbc.M608182200 BindingDB Entry DOI: 10.7270/Q2NK3C8N
					More data for this Ligand-Target Pair
cFMS -Tie-2 Chimera (Homo sapiens (Human))	BDBM17748 (2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...) Show SMILES Cc1cc2ncc(nc2cc1C)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N2O2/c1-9-5-12-13(6-10(9)2)18-14(8-17-12)11-3-4-15(19)16(20)7-11/h3-8,19-20H,1-2H3	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	7.5	22
Johnson & Johnson Pharmaceutical					Assay Description The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...				J Biol Chem 282: 4085-93 (2007) Article DOI: 10.1074/jbc.M608182200 BindingDB Entry DOI: 10.7270/Q2NK3C8N
					More data for this Ligand-Target Pair