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BDBM177755 US9120781, 18

SMILES: OC[C@H]1C[C@@H]2OC(=N[C@@H]2[C@@H](O)[C@@H]1O)N1CCC1

InChI Key: InChIKey=KFDDAZGHTBNRCQ-YUUAOHRVNA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177755   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-acetyl-beta-D-glucosaminidase (O-GlcNAcase)


(Homo sapiens (Human))
BDBM177755
PNG
(US9120781, 18)
Show SMILES OC[C@H]1C[C@@H]2OC(=N[C@@H]2[C@@H](O)[C@@H]1O)N1CCC1 |r,c:6|
Show InChI InChI=1/C11H18N2O4/c14-5-6-4-7-8(10(16)9(6)15)12-11(17-7)13-2-1-3-13/h6-10,14-16H,1-5H2/t6-,7+,8+,9-,10-/s2
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.130 -13.5n/an/an/an/an/a7.025



Simon Fraser University; Merck Sharp & Dohme Corp.; Alectos Therapeutics Inc.

US Patent


Assay Description
Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...


US Patent US9120781 (2015)


BindingDB Entry DOI: 10.7270/Q2DZ072S
More data for this
Ligand-Target Pair