BDBM177947 US9120797, 45
SMILES: CN(C)C1(CCC2(CC1)OCCc1c2[nH]c2ccc(O)cc12)c1ccccc1
InChI Key: InChIKey=KFKGRKGKOJKTPF-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM177947 (US9120797, 45) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.10 | -12.2 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Gruenenthal GmbH US Patent | Assay Description The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p... | US Patent US9120797 (2015) BindingDB Entry DOI: 10.7270/Q2X065T3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human)) | BDBM177947 (US9120797, 45) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.60 | -12.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Gruenenthal GmbH US Patent | Assay Description The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from... | US Patent US9120797 (2015) BindingDB Entry DOI: 10.7270/Q2X065T3 | |||||||||||
More data for this Ligand-Target Pair |