null

SMILES: CC(C)(C)C(=O)OCOC(=O)C1(CC=Cc2ccccc2)N2[C@@H](CC2=O)OC1=CC=O

InChI Key: InChIKey=RTZMBJMWCNEYEE-HUCLUGSFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 178199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (Escherichia coli)	BDBM178199 (US9120808, Example 19) Show SMILES CC(C)(C)C(=O)OCOC(=O)C1(CC=Cc2ccccc2)N2[C@@H](CC2=O)OC1=CC=O |w:13.12,28.31| Show InChI InChI=1S/C23H25NO7/c1-22(2,3)20(27)29-15-30-21(28)23(12-7-10-16-8-5-4-6-9-16)17(11-13-25)31-19-14-18(26)24(19)23/h4-11,13,19H,12,14-15H2,1-3H3/b10-7+,17-11-/t19-,23?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	7.0	37
NABRIVA THERAPEUTICS AG US Patent					Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...				US Patent US9120808 (2015) BindingDB Entry DOI: 10.7270/Q2Q81BT5
					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM178199 (US9120808, Example 19) Show SMILES CC(C)(C)C(=O)OCOC(=O)C1(CC=Cc2ccccc2)N2[C@@H](CC2=O)OC1=CC=O |w:13.12,28.31| Show InChI InChI=1S/C23H25NO7/c1-22(2,3)20(27)29-15-30-21(28)23(12-7-10-16-8-5-4-6-9-16)17(11-13-25)31-19-14-18(26)24(19)23/h4-11,13,19H,12,14-15H2,1-3H3/b10-7+,17-11-/t19-,23?/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	871	n/a	n/a	n/a	n/a	7.0	37
NABRIVA THERAPEUTICS AG US Patent					Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...				US Patent US9120808 (2015) BindingDB Entry DOI: 10.7270/Q2Q81BT5
					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Escherichia coli)	BDBM178199 (US9120808, Example 19) Show SMILES CC(C)(C)C(=O)OCOC(=O)C1(CC=Cc2ccccc2)N2[C@@H](CC2=O)OC1=CC=O |w:13.12,28.31| Show InChI InChI=1S/C23H25NO7/c1-22(2,3)20(27)29-15-30-21(28)23(12-7-10-16-8-5-4-6-9-16)17(11-13-25)31-19-14-18(26)24(19)23/h4-11,13,19H,12,14-15H2,1-3H3/b10-7+,17-11-/t19-,23?/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	617	n/a	n/a	n/a	n/a	7.0	37
NABRIVA THERAPEUTICS AG US Patent					Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...				US Patent US9120808 (2015) BindingDB Entry DOI: 10.7270/Q2Q81BT5
					More data for this Ligand-Target Pair