BDBM17854 3,5-Pyrazolediamine Inhibitor, 4::3-imino-4-[(E)-2-[2-(trifluoromethyl)phenyl]diazen-1-yl]-3H-pyrazol-5-amine

SMILES: FC(F)(F)c1ccccc1NN=c1c(=N)nnc1=N

InChI Key: InChIKey=AXVCAYVDTZRQAC-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17854   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase (Escherichia coli (strain K12))	BDBM17854 (3,5-Pyrazolediamine Inhibitor, 4 | 3-imino-4-[(E)-...) Show SMILES FC(F)(F)c1ccccc1NN=c1c(=N)nnc1=N |(-1.8,9.36,;-1.03,8.02,;.3,8.79,;-2.36,7.25,;-.26,6.69,;1.28,6.69,;2.05,5.36,;1.28,4.02,;-.26,4.02,;-1.03,5.36,;-2.57,5.36,;-3.34,4.02,;-4.88,4.02,;-6.13,4.93,;-6.13,6.47,;-7.37,4.02,;-6.9,2.56,;-5.35,2.56,;-4.45,1.31,)| Show InChI InChI=1S/C10H7F3N6/c11-10(12,13)5-3-1-2-4-6(5)16-17-7-8(14)18-19-9(7)15/h1-4,14-16H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	7.5	30
The Procter & Gamble Pharmaceuticals					Assay Description The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...				Proteins 66: 538-46 (2007) Article DOI: 10.1002/prot.21207 BindingDB Entry DOI: 10.7270/Q2MK6B5Q
					More data for this Ligand-Target Pair				3D Structure (crystal)