BDBM17864 Amino-Alcohol Inhibitor, 13::methyl (2S)-2-[(2S)-2-[(2S,3R)-3-amino-2-hydroxy-3-[4-(propan-2-yl)phenyl]propanamido]propanamido]-4-methylpentanoate
SMILES: COC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@@H](O)[C@H](N)c1ccc(cc1)C(C)C
InChI Key: InChIKey=WIWZNHHLFMPGGO-FZDIXFNVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Methionine aminopeptidase (Escherichia coli (strain K12)) | BDBM17864 (Amino-Alcohol Inhibitor, 13 | methyl (2S)-2-[(2S)-...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
The Procter & Gamble Pharmaceuticals | Assay Description The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an... | Proteins 66: 538-46 (2007) Article DOI: 10.1002/prot.21207 BindingDB Entry DOI: 10.7270/Q2MK6B5Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |