BDBM17868 (2S)-2-amino-4-(methylsulfanyl)-1-(pyridin-2-yl)butan-1-one::keto-heterocycle inhibitor, 2

SMILES: CSCC[C@H](N)C(=O)c1ccccn1

InChI Key: InChIKey=ARURVSWVWKOIIJ-QMMMGPOBSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (Staphylococcus aureus)	BDBM17868 ((2S)-2-amino-4-(methylsulfanyl)-1-(pyridin-2-yl)bu...) Show SMILES CSCC[C@H](N)C(=O)c1ccccn1 |r| Show InChI InChI=1S/C10H14N2OS/c1-14-7-5-8(11)10(13)9-4-2-3-6-12-9/h2-4,6,8H,5,7,11H2,1H3/t8-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.5	22
Morphochem AG					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				J Med Chem 47: 1325-8 (2004) Article DOI: 10.1021/jm034188j BindingDB Entry DOI: 10.7270/Q2GX48TV
					More data for this Ligand-Target Pair				3D Structure (crystal)