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SMILES: CC(C)(C)OC(=O)NC(C(=O)N1C[C@H]2[C@@H](C1C(=O)NC(C(=O)C(N)=O)C(C)(C)C)C2(C)C)C(C)(C)C

InChI Key: InChIKey=PXVZKSMODJNUCS-TZTQRCMZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17880   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus (HCV genotype 1a, isolate H))		BDBM17880
PNG
(Ketoamide inhibitor, 10 | tert-butyl N-{1-[(1R,5S)...)
Show SMILES CC(C)(C)OC(=O)NC(C(=O)N1C[C@H]2[C@@H](C1C(=O)NC(C(=O)C(N)=O)C(C)(C)C)C2(C)C)C(C)(C)C |r|
Show InChI InChI=1S/C26H44N4O6/c1-23(2,3)17(16(31)19(27)32)28-20(33)15-14-13(26(14,10)11)12-30(15)21(34)18(24(4,5)6)29-22(35)36-25(7,8)9/h13-15,17-18H,12H2,1-11H3,(H2,27,32)(H,28,33)(H,29,35)/t13-,14-,15?,17?,18?/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
>6.90E+4>-5.77n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...

J Med Chem 50: 2310-8 (2007)


Article DOI: 10.1021/jm060173k
BindingDB Entry DOI: 10.7270/Q27D2SDK
More data for this
Ligand-Target Pair