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SMILES: CC(C)CC(NC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)NC(CC1CCC1)C(=O)C(N)=O

InChI Key: InChIKey=ZMXJLHIWVKZBQT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17892   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus (HCV genotype 1a, isolate H))		BDBM17892
PNG
(Ketoamide inhibitor, 28 | tert-butyl N-[1-({1-[(1-...)
Show SMILES CC(C)CC(NC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)NC(CC1CCC1)C(=O)C(N)=O
Show InChI InChI=1S/C25H44N4O6/c1-14(2)12-17(21(32)27-16(18(30)20(26)31)13-15-10-9-11-15)28-22(33)19(24(3,4)5)29-23(34)35-25(6,7)8/h14-17,19H,9-13H2,1-8H3,(H2,26,31)(H,27,32)(H,28,33)(H,29,34)
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PC sid
UniChem

Similars
Article
PubMed
 1.50E+4n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...

J Med Chem 50: 2310-8 (2007)


Article DOI: 10.1021/jm060173k
BindingDB Entry DOI: 10.7270/Q27D2SDK
More data for this
Ligand-Target Pair