BDBM179277 US9125915, compound 10
SMILES: COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(NC(=O)CCc2ccccc2)cc1
InChI Key: InChIKey=OZHGOXVBHNGBBM-QHCPKHFHSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
H4-BRD4 (Homo sapiens (Human)) | BDBM179277 (US9125915, compound 10) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 47.1 | n/a | n/a | n/a | n/a | n/a | 25 |
Mitsubishi Tanabe Pharma Corporation US Patent | Assay Description An expression vector containing cDNA of BRD2, 3 and 4 added with Flag-tag was transfected to CHO cell, and a cell lysate was prepared 24 hr later. Bi... | US Patent US9125915 (2015) BindingDB Entry DOI: 10.7270/Q26972BJ | |||||||||||
More data for this Ligand-Target Pair |