BDBM179366 US9126957, 2
SMILES: C[C@H](O)[C@H]1C[C@@H]2OC(=N[C@@H]2[C@@H](O)[C@@H]1O)N(C)C
InChI Key: InChIKey=FZOKGSDDKBIICT-KIOSUUARSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM179366 (US9126957, 2) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.260 | -13.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
MERCK SHARP & DOHME CORP.; ALECTOS THERAPEUTICS, INC. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US9126957 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HN2 | |||||||||||
More data for this Ligand-Target Pair |