BDBM179625 US9127001, 6c::US9598410, Compound 6c
SMILES: CC(=O)N1CCc2c(C1)c(nn2Cc1cnccc1Cl)-c1cccc(c1)C(F)(F)F
InChI Key: InChIKey=KWPCBYXEFPXIAB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium channel subfamily K member 3 (Homo sapiens (Human)) | BDBM179625 (US9127001, 6c | US9598410, Compound 6c) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 215 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA... | US Patent US9598410 (2017) BindingDB Entry DOI: 10.7270/Q2377BRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium channel subfamily K member 3 (Homo sapiens (Human)) | BDBM179625 (US9127001, 6c | US9598410, Compound 6c) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 215 | n/a | n/a | n/a | n/a | n/a | 25 |
Sanofi US Patent | Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,... | US Patent US9127001 (2015) BindingDB Entry DOI: 10.7270/Q2HM576Z | |||||||||||
More data for this Ligand-Target Pair |