BDBM179629 US9127001, 6g::US9598410, Compound 6g

SMILES: CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1)-c1cccc(n1)C(F)(F)F

InChI Key: InChIKey=FWEYOUTVRSDFHI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179629 (US9127001, 6g | US9598410, Compound 6g) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1)-c1cccc(n1)C(F)(F)F Show InChI InChI=1S/C21H18F4N4O/c1-13(30)28-10-9-18-16(12-28)20(17-3-2-4-19(26-17)21(23,24)25)27-29(18)11-14-5-7-15(22)8-6-14/h2-8H,9-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	99.5	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...				US Patent US9598410 (2017) BindingDB Entry DOI: 10.7270/Q2377BRM
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179629 (US9127001, 6g | US9598410, Compound 6g) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1)-c1cccc(n1)C(F)(F)F Show InChI InChI=1S/C21H18F4N4O/c1-13(30)28-10-9-18-16(12-28)20(17-3-2-4-19(26-17)21(23,24)25)27-29(18)11-14-5-7-15(22)8-6-14/h2-8H,9-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	99.5	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9127001 (2015) BindingDB Entry DOI: 10.7270/Q2HM576Z
					More data for this Ligand-Target Pair