BDBM179630 US9127001, 6h::US9598410, Compound 6h

SMILES: CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1cc(ccn1)C(F)(F)F

InChI Key: InChIKey=IHQJWODJNXYUPX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179630 (US9127001, 6h | US9598410, Compound 6h) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1cc(ccn1)C(F)(F)F Show InChI InChI=1S/C21H17F5N4O/c1-12(31)29-7-5-19-16(11-29)20(18-8-14(4-6-27-18)21(24,25)26)28-30(19)10-13-2-3-15(22)9-17(13)23/h2-4,6,8-9H,5,7,10-11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...				US Patent US9598410 (2017) BindingDB Entry DOI: 10.7270/Q2377BRM
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179630 (US9127001, 6h | US9598410, Compound 6h) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1cc(ccn1)C(F)(F)F Show InChI InChI=1S/C21H17F5N4O/c1-12(31)29-7-5-19-16(11-29)20(18-8-14(4-6-27-18)21(24,25)26)28-30(19)10-13-2-3-15(22)9-17(13)23/h2-4,6,8-9H,5,7,10-11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9127001 (2015) BindingDB Entry DOI: 10.7270/Q2HM576Z
					More data for this Ligand-Target Pair