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BDBM179646 US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyridin-2-yl)phenol dihydrochloride::US9676701, 21 3-(5-((trans)-2-aminocyclopropyl)pyridin-2-yl)phenol[a2]

SMILES: N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(O)c1

InChI Key: InChIKey=NZVNIKNQTCIVQN-QWAQRTLVNA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 179646   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM179646
PNG
(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(O)c1 |r|
Show InChI InChI=1/C14H14N2O/c15-13-7-12(13)10-4-5-14(16-8-10)9-2-1-3-11(17)6-9/h1-6,8,12-13,17H,7,15H2/t12-,13+/s2
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
50 -9.95n/an/an/an/an/a7.425



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM179646
PNG
(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(O)c1 |r|
Show InChI InChI=1/C14H14N2O/c15-13-7-12(13)10-4-5-14(16-8-10)9-2-1-3-11(17)6-9/h1-6,8,12-13,17H,7,15H2/t12-,13+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
50 -9.95n/an/an/an/an/a7.425



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM179646
PNG
(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(O)c1 |r|
Show InChI InChI=1/C14H14N2O/c15-13-7-12(13)10-4-5-14(16-8-10)9-2-1-3-11(17)6-9/h1-6,8,12-13,17H,7,15H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
>1.00E+3n/an/an/an/an/an/a7.5n/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM179646
PNG
(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(O)c1 |r|
Show InChI InChI=1/C14H14N2O/c15-13-7-12(13)10-4-5-14(16-8-10)9-2-1-3-11(17)6-9/h1-6,8,12-13,17H,7,15H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
>1.00E+3n/an/an/an/an/an/a7.5n/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM179646
PNG
(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(O)c1 |r|
Show InChI InChI=1/C14H14N2O/c15-13-7-12(13)10-4-5-14(16-8-10)9-2-1-3-11(17)6-9/h1-6,8,12-13,17H,7,15H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
>1.00E+3n/an/an/an/an/an/a7.5n/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM179646
PNG
(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(O)c1 |r|
Show InChI InChI=1/C14H14N2O/c15-13-7-12(13)10-4-5-14(16-8-10)9-2-1-3-11(17)6-9/h1-6,8,12-13,17H,7,15H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
>1.00E+3n/an/an/an/an/an/a7.5n/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair