BDBM179713 US9127001, 8t::US9598410, Compound 8t

SMILES: Fc1ccc(Cn2nc(c3CN(CCc23)C(=O)c2ccccn2)-c2cccc(c2)C#N)c(F)c1

InChI Key: InChIKey=YCWFDGKXOJUWRW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179713 (US9127001, 8t | US9598410, Compound 8t) Show SMILES Fc1ccc(Cn2nc(c3CN(CCc23)C(=O)c2ccccn2)-c2cccc(c2)C#N)c(F)c1 Show InChI InChI=1S/C26H19F2N5O/c27-20-8-7-19(22(28)13-20)15-33-24-9-11-32(26(34)23-6-1-2-10-30-23)16-21(24)25(31-33)18-5-3-4-17(12-18)14-29/h1-8,10,12-13H,9,11,15-16H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	246	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...				US Patent US9598410 (2017) BindingDB Entry DOI: 10.7270/Q2377BRM
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179713 (US9127001, 8t | US9598410, Compound 8t) Show SMILES Fc1ccc(Cn2nc(c3CN(CCc23)C(=O)c2ccccn2)-c2cccc(c2)C#N)c(F)c1 Show InChI InChI=1S/C26H19F2N5O/c27-20-8-7-19(22(28)13-20)15-33-24-9-11-32(26(34)23-6-1-2-10-30-23)16-21(24)25(31-33)18-5-3-4-17(12-18)14-29/h1-8,10,12-13H,9,11,15-16H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	246	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9127001 (2015) BindingDB Entry DOI: 10.7270/Q2HM576Z
					More data for this Ligand-Target Pair