BDBM179745 US9676701, 56 5-(5-((trans)-2-aminocyclopropyl)pyridin-2-yl)thiophene-2-carbonitrile hydrochloride

SMILES: N[C@H]1C[C@@H]1c1ccc(nc1)-c1ccc(s1)C#N

InChI Key: InChIKey=WXFIDYNVFUVCJP-MNOVXSKESA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM179745 (US9676701, 56 5-(5-((trans)-2-aminocyclopropyl)pyr...) Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1ccc(s1)C#N |r| Show InChI InChI=1S/C13H11N3S/c14-6-9-2-4-13(17-9)12-3-1-8(7-16-12)10-5-11(10)15/h1-4,7,10-11H,5,15H2/t10-,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	50	-9.95	n/a	n/a	n/a	n/a	n/a	7.4	25
ORYZON GENOMICS, S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM179745 (US9676701, 56 5-(5-((trans)-2-aminocyclopropyl)pyr...) Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1ccc(s1)C#N |r| Show InChI InChI=1S/C13H11N3S/c14-6-9-2-4-13(17-9)12-3-1-8(7-16-12)10-5-11(10)15/h1-4,7,10-11H,5,15H2/t10-,11+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM179745 (US9676701, 56 5-(5-((trans)-2-aminocyclopropyl)pyr...) Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1ccc(s1)C#N |r| Show InChI InChI=1S/C13H11N3S/c14-6-9-2-4-13(17-9)12-3-1-8(7-16-12)10-5-11(10)15/h1-4,7,10-11H,5,15H2/t10-,11+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair