BDBM179829 US9676701, 65 N-(3-(5-((trans)-2-aminocyclopropyl)pyridin-2-yl)phenyl)propane-2-sulfonamide hydrochloride

SMILES: CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1N

InChI Key: InChIKey=WMECSKVEJLNNAW-CVEARBPZSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM179829 (US9676701, 65 N-(3-(5-((trans)-2-aminocyclopropyl)...) Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1N |r| Show InChI InChI=1S/C17H21N3O2S/c1-11(2)23(21,22)20-14-5-3-4-12(8-14)17-7-6-13(10-19-17)15-9-16(15)18/h3-8,10-11,15-16,20H,9,18H2,1-2H3/t15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	50	-9.95	n/a	n/a	n/a	n/a	n/a	7.4	25
ORYZON GENOMICS, S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM179829 (US9676701, 65 N-(3-(5-((trans)-2-aminocyclopropyl)...) Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1N |r| Show InChI InChI=1S/C17H21N3O2S/c1-11(2)23(21,22)20-14-5-3-4-12(8-14)17-7-6-13(10-19-17)15-9-16(15)18/h3-8,10-11,15-16,20H,9,18H2,1-2H3/t15-,16+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM179829 (US9676701, 65 N-(3-(5-((trans)-2-aminocyclopropyl)...) Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1N |r| Show InChI InChI=1S/C17H21N3O2S/c1-11(2)23(21,22)20-14-5-3-4-12(8-14)17-7-6-13(10-19-17)15-9-16(15)18/h3-8,10-11,15-16,20H,9,18H2,1-2H3/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair