BDBM179866 US9132129, Cpd047

SMILES: CCCC(C(O)=O)c1c(C)nc2c3ccccc3nn2c1-c1ccc(C)cc1

InChI Key: InChIKey=ZCHVIKJTLWPNBL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179866   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
lens epithelium-derived growth factor p75 (Homo sapiens (Human))	BDBM179866 (US9132129, Cpd047) Show SMILES CCCC(C(O)=O)c1c(C)nc2c3ccccc3nn2c1-c1ccc(C)cc1 Show InChI InChI=1S/C23H23N3O2/c1-4-7-18(23(27)28)20-15(3)24-22-17-8-5-6-9-19(17)25-26(22)21(20)16-12-10-14(2)11-13-16/h5-6,8-13,18H,4,7H2,1-3H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	7.0	25
KATHOLIEKE UNIVERSITEIT LEUVEN US Patent					Assay Description An Homogeneous Time Resolved Fluorescence (HTRF) assay was performed in a manner similar to previous reports on HTRF protein protein assays as review...				US Patent US9132129 (2015) BindingDB Entry DOI: 10.7270/Q2MC8XSH
					More data for this Ligand-Target Pair
lens epithelium-derived growth factor p75 (Homo sapiens (Human))	BDBM179866 (US9132129, Cpd047) Show SMILES CCCC(C(O)=O)c1c(C)nc2c3ccccc3nn2c1-c1ccc(C)cc1 Show InChI InChI=1S/C23H23N3O2/c1-4-7-18(23(27)28)20-15(3)24-22-17-8-5-6-9-19(17)25-26(22)21(20)16-12-10-14(2)11-13-16/h5-6,8-13,18H,4,7H2,1-3H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.85E+3	n/a	n/a	n/a	n/a	7.4	4
KATHOLIEKE UNIVERSITEIT LEUVEN US Patent					Assay Description An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...				US Patent US9132129 (2015) BindingDB Entry DOI: 10.7270/Q2MC8XSH
					More data for this Ligand-Target Pair