BDBM179906 US9676701, 101 N-(3-(5-((trans)-2-aminocyclopropyl)pyridin-2-yl)phenyl)-2-cyanobenzenesulfonamide hydrochloride

SMILES: N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(NS(=O)(=O)c2ccccc2C#N)c1

InChI Key: InChIKey=CQARUEXTPAIHPL-MOPGFXCFSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM179906 (US9676701, 101 N-(3-(5-((trans)-2-aminocyclopropyl...) Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(NS(=O)(=O)c2ccccc2C#N)c1 |r| Show InChI InChI=1S/C21H18N4O2S/c22-12-15-4-1-2-7-21(15)28(26,27)25-17-6-3-5-14(10-17)20-9-8-16(13-24-20)18-11-19(18)23/h1-10,13,18-19,25H,11,23H2/t18-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	50	-9.95	n/a	n/a	n/a	n/a	n/a	7.4	25
ORYZON GENOMICS, S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM179906 (US9676701, 101 N-(3-(5-((trans)-2-aminocyclopropyl...) Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(NS(=O)(=O)c2ccccc2C#N)c1 |r| Show InChI InChI=1S/C21H18N4O2S/c22-12-15-4-1-2-7-21(15)28(26,27)25-17-6-3-5-14(10-17)20-9-8-16(13-24-20)18-11-19(18)23/h1-10,13,18-19,25H,11,23H2/t18-,19+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM179906 (US9676701, 101 N-(3-(5-((trans)-2-aminocyclopropyl...) Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(NS(=O)(=O)c2ccccc2C#N)c1 |r| Show InChI InChI=1S/C21H18N4O2S/c22-12-15-4-1-2-7-21(15)28(26,27)25-17-6-3-5-14(10-17)20-9-8-16(13-24-20)18-11-19(18)23/h1-10,13,18-19,25H,11,23H2/t18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...				US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN
					More data for this Ligand-Target Pair