BDBM179976 US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)thiazol-2-yl)phenol hydrochloride
SMILES: N[C@H]1C[C@@H]1c1cnc(s1)-c1cccc(O)c1
InChI Key: InChIKey=JRNQFIYVQYTRHZ-UWVGGRQHSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM179976 (US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)th...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 50 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
ORYZON GENOMICS, S.A. US Patent | Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5... | US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM179976 (US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)th...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 50 | -9.95 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
ORYZON GENOMICS, S.A. US Patent | Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e.... | US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM179976 (US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)th...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
ORYZON GENOMICS, S.A. US Patent | Assay Description Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5... | US Patent US9676701 (2017) BindingDB Entry DOI: 10.7270/Q27P8WJN | |||||||||||
More data for this Ligand-Target Pair |