Found 2 hits for monomerid = 180711 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM180711
(US8829029, 11)Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2ccc(cc2)N2CCS(=O)(=O)CC2)CC1 |r,wU:19.24,wD:16.17,(-4.9,-7.48,;-5.3,-5.99,;-4.21,-4.9,;-4.61,-3.41,;-6.1,-3.01,;-6.49,-1.53,;-7.98,-1.13,;-8.67,-3.7,;-7.18,-4.1,;-6.79,-5.59,;-5.41,-.44,;-3.92,-.84,;-2.83,.25,;-3.23,1.74,;-2.14,2.83,;-.65,2.43,;.44,3.52,;1.93,3.12,;3.01,4.21,;2.62,5.7,;1.13,6.1,;.04,5.01,;3.7,6.79,;5.19,6.39,;6.28,7.48,;5.59,4.9,;4.5,3.81,;4.9,2.32,;6.39,1.93,;7.48,3.01,;7.08,4.5,;6.79,.44,;5.7,-.65,;6.1,-2.14,;7.58,-2.54,;7.18,-4.02,;8.67,-3.63,;8.67,-1.45,;8.27,.04,;-4.72,2.14,;-5.8,1.05,)| Show InChI InChI=1S/C31H39FN4O4S/c32-25-5-10-28-29(21-25)40-34-30(28)23-12-15-35(16-13-23)14-11-22-1-6-26(7-2-22)33-31(37)24-3-8-27(9-4-24)36-17-19-41(38,39)20-18-36/h3-5,8-10,21-23,26H,1-2,6-7,11-20H2,(H,33,37)/t22-,26- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 2.48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc.
US Patent
| Assay Description Aliquots of membrane preparations were thawed at RT, resuspended in assay buffer (D2, D3: 50 mM Tris-HCl, 120 mM NaCl, 5 mM MgCl2, 1 mM EDTA, 5 mM KC... |
US Patent US8829029 (2014)
BindingDB Entry DOI: 10.7270/Q22B8WSS |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM180711
(US8829029, 11)Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2ccc(cc2)N2CCS(=O)(=O)CC2)CC1 |r,wU:19.24,wD:16.17,(-4.9,-7.48,;-5.3,-5.99,;-4.21,-4.9,;-4.61,-3.41,;-6.1,-3.01,;-6.49,-1.53,;-7.98,-1.13,;-8.67,-3.7,;-7.18,-4.1,;-6.79,-5.59,;-5.41,-.44,;-3.92,-.84,;-2.83,.25,;-3.23,1.74,;-2.14,2.83,;-.65,2.43,;.44,3.52,;1.93,3.12,;3.01,4.21,;2.62,5.7,;1.13,6.1,;.04,5.01,;3.7,6.79,;5.19,6.39,;6.28,7.48,;5.59,4.9,;4.5,3.81,;4.9,2.32,;6.39,1.93,;7.48,3.01,;7.08,4.5,;6.79,.44,;5.7,-.65,;6.1,-2.14,;7.58,-2.54,;7.18,-4.02,;8.67,-3.63,;8.67,-1.45,;8.27,.04,;-4.72,2.14,;-5.8,1.05,)| Show InChI InChI=1S/C31H39FN4O4S/c32-25-5-10-28-29(21-25)40-34-30(28)23-12-15-35(16-13-23)14-11-22-1-6-26(7-2-22)33-31(37)24-3-8-27(9-4-24)36-17-19-41(38,39)20-18-36/h3-5,8-10,21-23,26H,1-2,6-7,11-20H2,(H,33,37)/t22-,26- | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 4.67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc.
US Patent
| Assay Description Aliquots of membrane preparations were thawed at RT, resuspended in assay buffer (D2, D3: 50 mM Tris-HCl, 120 mM NaCl, 5 mM MgCl2, 1 mM EDTA, 5 mM KC... |
US Patent US8829029 (2014)
BindingDB Entry DOI: 10.7270/Q22B8WSS |
More data for this Ligand-Target Pair | |