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SMILES: O=S(=O)(c1ccc(CNC(Nc2ccncc2)=NC#N)cc1)c1cnc2ccccc2c1

InChI Key: InChIKey=KBVAFKKCBRMSJL-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180928   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nicotinamide phosphoribosyltransferase


(Homo sapiens (Human))		BDBM180928
PNG
(US9676721, 97 2-cyano-3-(pyridin-4-yl)-1-{[4-(quin...)
Show SMILES O=S(=O)(c1ccc(CNC(Nc2ccncc2)=NC#N)cc1)c1cnc2ccccc2c1 |w:17.18|
Show InChI InChI=1S/C23H18N6O2S/c24-16-28-23(29-19-9-11-25-12-10-19)27-14-17-5-7-20(8-6-17)32(30,31)21-13-18-3-1-2-4-22(18)26-15-21/h1-13,15H,14H2,(H2,25,27,28,29)
PDB
MMDB

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US Patent
n/an/a 1n/an/an/an/a7.525



FORMA TM, LLC

US Patent


Assay Description
The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...

US Patent US9676721 (2017)


BindingDB Entry DOI: 10.7270/Q2VD6WMM
More data for this
Ligand-Target Pair