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SMILES: Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCN(C4CCCCC4)C3=O)nc2)ccn1

InChI Key: InChIKey=KFDMABXQUQMQTQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 181019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor [538-972] (Homo sapiens (Human))	BDBM181019 (US9133183, Example 15) Show SMILES Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCN(C4CCCCC4)C3=O)nc2)ccn1 Show InChI InChI=1S/C24H27N7O3/c1-29-16-17(14-27-29)21-13-19(9-10-25-21)34-20-7-8-22(26-15-20)28-23(32)31-12-11-30(24(31)33)18-5-3-2-4-6-18/h7-10,13-16,18H,2-6,11-12H2,1H3,(H,26,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	30
Deciphera Pharmaceuticals, LLC US Patent					Assay Description Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...				US Patent US9133183 (2015) BindingDB Entry DOI: 10.7270/Q2DN43TD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM181019 (US9133183, Example 15) Show SMILES Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCN(C4CCCCC4)C3=O)nc2)ccn1 Show InChI InChI=1S/C24H27N7O3/c1-29-16-17(14-27-29)21-13-19(9-10-25-21)34-20-7-8-22(26-15-20)28-23(32)31-12-11-30(24(31)33)18-5-3-2-4-6-18/h7-10,13-16,18H,2-6,11-12H2,1H3,(H,26,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	27
Deciphera Pharmaceuticals, LLC US Patent					Assay Description These tests measure the ability of compounds to inhibit the enzymatic activity of recombinant human c-Met/HGF receptor and VEGF receptor enzymatic ac...				US Patent US9133183 (2015) BindingDB Entry DOI: 10.7270/Q2DN43TD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM181019 (US9133183, Example 15) Show SMILES Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCN(C4CCCCC4)C3=O)nc2)ccn1 Show InChI InChI=1S/C24H27N7O3/c1-29-16-17(14-27-29)21-13-19(9-10-25-21)34-20-7-8-22(26-15-20)28-23(32)31-12-11-30(24(31)33)18-5-3-2-4-6-18/h7-10,13-16,18H,2-6,11-12H2,1H3,(H,26,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	27
Deciphera Pharmaceuticals, LLC US Patent					Assay Description These tests measure the ability of compounds to inhibit the enzymatic activity of recombinant human c-Met/HGF receptor and VEGF receptor enzymatic ac...				US Patent US9133183 (2015) BindingDB Entry DOI: 10.7270/Q2DN43TD
					More data for this Ligand-Target Pair