BDBM181049 NR9
SMILES: O=C1N=C(NCc2cccs2)S\C1=C/c1ccc2ncccc2c1
InChI Key: InChIKey=XOLMRFUGOINFDQ-YBEGLDIGSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificty protein kinase CLK1 (Homo sapiens (Human)) | BDBM181049 (NR9) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London | Assay Description For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c... | Biochemistry 55: 608-17 (2016) Article DOI: 10.1021/acs.biochem.5b01128 BindingDB Entry DOI: 10.7270/Q2N58K5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human)) | BDBM181049 (NR9) | PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 596 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London | Assay Description For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c... | Biochemistry 55: 608-17 (2016) Article DOI: 10.1021/acs.biochem.5b01128 BindingDB Entry DOI: 10.7270/Q2N58K5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDC2-like kinase 3 (CLK3) (Homo sapiens (Human)) | BDBM181049 (NR9) | PDB B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London | Assay Description For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c... | Biochemistry 55: 608-17 (2016) Article DOI: 10.1021/acs.biochem.5b01128 BindingDB Entry DOI: 10.7270/Q2N58K5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK2 (Homo sapiens (Human)) | BDBM181049 (NR9) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 553 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London | Assay Description For kinase inhibition assays, the final concentrations of the enzymes were 15, 14.5, 14.5, and 8.8 nM for CLK1, CLK2, CLK3, and Dyrk1A (Invitrogen, c... | Biochemistry 55: 608-17 (2016) Article DOI: 10.1021/acs.biochem.5b01128 BindingDB Entry DOI: 10.7270/Q2N58K5J | |||||||||||
More data for this Ligand-Target Pair |