null

SMILES: NCC(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key: InChIKey=AMWPZASLDLLQFT-JJNLEZRASA-N

PDB links: 9 PDB IDs match this monomer. 25 PDB IDs contain this monomer as substructures. 25 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine--tRNA ligase (Bombyx mori)	BDBM18138 (2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-...) Show SMILES NCC(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C12H17N7O7S/c13-1-6(20)18-27(23,24)25-2-5-8(21)9(22)12(26-5)19-4-17-7-10(14)15-3-16-11(7)19/h3-5,8-9,12,21-22H,1-2,13H2,(H,18,20)(H2,14,15,16)/t5-,8-,9-,12-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	50	-9.95	2.00E+3	270	n/a	n/a	n/a	7.5	25
Medical College of Ohio					Assay Description Aminoacyl-tRNA synthetase assays were measuring the incorporation of [14C] amino acid into tRNA.				Biochemistry 42: 5333-40 (2003) Article DOI: 10.1021/bi030031h BindingDB Entry DOI: 10.7270/Q2HQ3X6H
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 18138

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
tRNA synthetase (GlyRS) (Bombyx mori)	BDBM18138 (2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-...)	GoogleScholar	MMDB PC cid PC sid PDB		-8.93	35.6	-44.7	6.57	7.20	24.9
Medical College of Ohio					Biochemistry 42: 5333-40 (2003)