BDBM181743 US9139585, 33
SMILES: OC(CN1CCN(CCc2ccc3C(=O)OCCc3c2)CC1)c1ccc2C(=O)OCc2c1C(F)(F)F
InChI Key: InChIKey=YKCREZLXMYSMST-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human)) | BDBM181743 (US9139585, 33) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 38 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu... | US Patent US9139585 (2015) BindingDB Entry DOI: 10.7270/Q29P30F8 | |||||||||||
More data for this Ligand-Target Pair |