BDBM181802 US9145380, 5

SMILES: NS(=O)(=O)c1ccc(F)cc1NS(=O)(=O)\C=C\c1ccc(cc1)-c1cc2ccccc2o1

InChI Key: InChIKey=RMYDADGWCAXZGR-VAWYXSNFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase 2 (Homo sapiens (Human))	BDBM181802 (US9145380, 5) Show SMILES NS(=O)(=O)c1ccc(F)cc1NS(=O)(=O)\C=C\c1ccc(cc1)-c1cc2ccccc2o1 Show InChI InChI=1S/C22H17FN2O5S2/c23-18-9-10-22(32(24,28)29)19(14-18)25-31(26,27)12-11-15-5-7-16(8-6-15)21-13-17-3-1-2-4-20(17)30-21/h1-14,25H,(H2,24,28,29)/b12-11+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	6.8	n/a
Astrazeneca AB US Patent					Assay Description A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...				US Patent US9145380 (2015) BindingDB Entry DOI: 10.7270/Q2XG9PXM
					More data for this Ligand-Target Pair