BDBM181833 US9145380, 36
SMILES: NS(=O)(=O)c1c(F)cccc1NS(=O)(=O)\C=C\c1ccc(cc1)-c1ccco1
InChI Key: InChIKey=KDOXJJPEZQAITK-ZRDIBKRKSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase 2 (Homo sapiens (Human)) | BDBM181833 (US9145380, 36) | PDB B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 57 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Astrazeneca AB US Patent | Assay Description A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp... | US Patent US9145380 (2015) BindingDB Entry DOI: 10.7270/Q2XG9PXM | |||||||||||
More data for this Ligand-Target Pair |