BDBM181889 US9145380, 92

SMILES: NS(=O)(=O)c1ccc(F)cc1NS(=O)(=O)\C=C\c1ccc2ccccc2c1

InChI Key: InChIKey=LZFJNDKMICVCEA-MDZDMXLPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase 2 (Homo sapiens (Human))	BDBM181889 (US9145380, 92) Show SMILES NS(=O)(=O)c1ccc(F)cc1NS(=O)(=O)\C=C\c1ccc2ccccc2c1 Show InChI InChI=1S/C18H15FN2O4S2/c19-16-7-8-18(27(20,24)25)17(12-16)21-26(22,23)10-9-13-5-6-14-3-1-2-4-15(14)11-13/h1-12,21H,(H2,20,24,25)/b10-9+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	91	n/a	n/a	n/a	n/a	6.8	n/a
Astrazeneca AB US Patent					Assay Description A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...				US Patent US9145380 (2015) BindingDB Entry DOI: 10.7270/Q2XG9PXM
					More data for this Ligand-Target Pair