BDBM182009 US9145380, 212

SMILES: NS(=O)(=O)c1cc(CO)ccc1NS(=O)(=O)CCc1ccc(cc1)C#CC1CCCC1

InChI Key: InChIKey=RTLWKJXLJUKQCS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase 2 (Homo sapiens (Human))	BDBM182009 (US9145380, 212) Show SMILES NS(=O)(=O)c1cc(CO)ccc1NS(=O)(=O)CCc1ccc(cc1)C#CC1CCCC1 Show InChI InChI=1S/C22H26N2O5S2/c23-31(28,29)22-15-20(16-25)11-12-21(22)24-30(26,27)14-13-19-9-7-18(8-10-19)6-5-17-3-1-2-4-17/h7-12,15,17,24-25H,1-4,13-14,16H2,(H2,23,28,29)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	6.8	n/a
Astrazeneca AB US Patent					Assay Description A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...				US Patent US9145380 (2015) BindingDB Entry DOI: 10.7270/Q2XG9PXM
					More data for this Ligand-Target Pair