BDBM18203 1,3-diethyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, 10j

SMILES: CCC1CN(CC)c2cc3c(cc(=O)[nH]c3cc2O1)C(F)(F)F

InChI Key: InChIKey=LLGNUOUFJSRIQB-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM18203 (1,3-diethyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-qui...) Show SMILES CCC1CN(CC)c2cc3c(cc(=O)[nH]c3cc2O1)C(F)(F)F Show InChI InChI=1S/C16H17F3N2O2/c1-3-9-8-21(4-2)13-5-10-11(16(17,18)19)6-15(22)20-12(10)7-14(13)23-9/h5-7,9H,3-4,8H2,1-2H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	34	-10.6	n/a	n/a	31	n/a	n/a	7.4	37
Ligand Pharmaceuticals Inc.					Assay Description The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...				J Med Chem 50: 2486-96 (2007) Article DOI: 10.1021/jm061329j BindingDB Entry DOI: 10.7270/Q20R9MNK
					More data for this Ligand-Target Pair