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BDBM182710 US9145402, 17

SMILES: CNc1nc(Nc2ccc(cc2OCCF)S(C)(=O)=O)ncc1Cl

InChI Key: InChIKey=APLNOTQKAPXFAR-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182710   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)


(Homo sapiens (Human))
BDBM182710
PNG
(US9145402, 17)
Show SMILES CNc1nc(Nc2ccc(cc2OCCF)S(C)(=O)=O)ncc1Cl
Show InChI InChI=1S/C14H16ClFN4O3S/c1-17-13-10(15)8-18-14(20-13)19-11-4-3-9(24(2,21)22)7-12(11)23-6-5-16/h3-4,7-8H,5-6H2,1-2H3,(H2,17,18,19,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem

Similars

US Patent
12n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...


US Patent US9145402 (2015)


BindingDB Entry DOI: 10.7270/Q2J67FQ3
More data for this
Ligand-Target Pair