BDBM182712 US9145402, 19

SMILES: CNc1nc(Nc2ccc(cc2OCCF)S(C)(=O)=O)ncc1C(F)(F)F

InChI Key: InChIKey=PVYVRIRIIGCUKO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM182712 (US9145402, 19) Show SMILES CNc1nc(Nc2ccc(cc2OCCF)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C15H16F4N4O3S/c1-20-13-10(15(17,18)19)8-21-14(23-13)22-11-4-3-9(27(2,24)25)7-12(11)26-6-5-16/h3-4,7-8H,5-6H2,1-2H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US9145402 (2015) BindingDB Entry DOI: 10.7270/Q2J67FQ3
					More data for this Ligand-Target Pair