BDBM182717 US9145402, 24

SMILES: CNc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl

InChI Key: InChIKey=LZNKQRLLXOCSJT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM182717 (US9145402, 24) Show SMILES CNc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl Show InChI InChI=1S/C16H20ClN5O2/c1-18-15-12(17)10-19-16(21-15)20-13-4-3-11(9-14(13)23-2)22-5-7-24-8-6-22/h3-4,9-10H,5-8H2,1-2H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US9145402 (2015) BindingDB Entry DOI: 10.7270/Q2J67FQ3
					More data for this Ligand-Target Pair