BDBM182731 US9145402, 38

SMILES: CCNc1nc(Nc2ccc(c3OCCOc23)S(C)(=O)=O)ncc1C(F)(F)F

InChI Key: InChIKey=HYZJXVODIRZJGT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM182731 (US9145402, 38) Show SMILES CCNc1nc(Nc2ccc(c3OCCOc23)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C16H17F3N4O4S/c1-3-20-14-9(16(17,18)19)8-21-15(23-14)22-10-4-5-11(28(2,24)25)13-12(10)26-6-7-27-13/h4-5,8H,3,6-7H2,1-2H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US9145402 (2015) BindingDB Entry DOI: 10.7270/Q2J67FQ3
					More data for this Ligand-Target Pair