BDBM182767 US9145414, 17::US9145414, 9
SMILES: CCn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)nnc3C(N)=O)cccc12
InChI Key: InChIKey=RPHUUBHXCXCDPM-DZGCQCFKSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM182767 (US9145414, 17 | US9145414, 9) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | 7.5 | 25 |
TAIHO PHARMACEUTICAL CO., LTD. US Patent | Assay Description The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the... | US Patent US9145414 (2015) BindingDB Entry DOI: 10.7270/Q2513X18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM182767 (US9145414, 17 | US9145414, 9) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.4 | 25 |
TAIHO PHARMACEUTICAL CO., LTD. US Patent | Assay Description The in vitro inhibitory activity of the compound against Aurora B kinase activity was assayed with reference to a method described in patent public... | US Patent US9145414 (2015) BindingDB Entry DOI: 10.7270/Q2513X18 | |||||||||||
More data for this Ligand-Target Pair |