null
SMILES: N[C@H]1CCCC[C@H]1Nc1nnc(C(N)=O)c(Nc2csc3ccccc23)n1
InChI Key: InChIKey=KLZNVMDVASBUQX-NWDGAFQWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM182805 (US9145414, 212) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | 7.5 | 25 |
TAIHO PHARMACEUTICAL CO., LTD. US Patent | Assay Description The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the... | US Patent US9145414 (2015) BindingDB Entry DOI: 10.7270/Q2513X18 | |||||||||||
More data for this Ligand-Target Pair |