null

SMILES: CN(C)C1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2ccc(F)c(F)c2)C2CCCCC2)CC1

InChI Key: InChIKey=QPDFWFQRIFSVFV-RPLLCQBOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM182823 (US9145418, 6) Show SMILES CN(C)C1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2ccc(F)c(F)c2)C2CCCCC2)CC1 Show InChI InChI=1S/C30H41F2N5O2/c1-35(2)23-10-12-36(13-11-23)19-27(20-6-4-3-5-7-20)34-29(38)16-24-17-33-30(39)28-15-22(18-37(24)28)21-8-9-25(31)26(32)14-21/h8-9,14-15,18,20,23-24,27H,3-7,10-13,16-17,19H2,1-2H3,(H,33,39)(H,34,38)/t24-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	171	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description Method for PIM2 Kinase Inhibition Assay: Dowex Techniquei. Kinase Buffer (KB)The buffer for PIM2 assay was composed of HEPES 50 mM, at pH 7.5, with 1...				US Patent US9145418 (2015) BindingDB Entry DOI: 10.7270/Q218359X
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM182823 (US9145418, 6) Show SMILES CN(C)C1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2ccc(F)c(F)c2)C2CCCCC2)CC1 Show InChI InChI=1S/C30H41F2N5O2/c1-35(2)23-10-12-36(13-11-23)19-27(20-6-4-3-5-7-20)34-29(38)16-24-17-33-30(39)28-15-22(18-37(24)28)21-8-9-25(31)26(32)14-21/h8-9,14-15,18,20,23-24,27H,3-7,10-13,16-17,19H2,1-2H3,(H,33,39)(H,34,38)/t24-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	3.0	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with .sup.33P-....				US Patent US9145418 (2015) BindingDB Entry DOI: 10.7270/Q218359X
					More data for this Ligand-Target Pair