BDBM183016 US9150544, 50

SMILES: CN(C)c1ncc(s1)S(=O)(=O)N[C@H]1CCN([C@H](Cc2cc3ccnc(N)c3cc2Cl)C(O)=O)C1=O

InChI Key: InChIKey=DYRGULRRGUHACC-JKSUJKDBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 183016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM183016 (US9150544, 50) Show SMILES CN(C)c1ncc(s1)S(=O)(=O)N[C@H]1CCN([C@H](Cc2cc3ccnc(N)c3cc2Cl)C(O)=O)C1=O |r| Show InChI InChI=1S/C21H23ClN6O5S2/c1-27(2)21-25-10-17(34-21)35(32,33)26-15-4-6-28(19(15)29)16(20(30)31)8-12-7-11-3-5-24-18(23)13(11)9-14(12)22/h3,5,7,9-10,15-16,26H,4,6,8H2,1-2H3,(H2,23,24)(H,30,31)/t15-,16+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.0	n/a
Sanofi US Patent					Assay Description The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...				US Patent US9150544 (2015) BindingDB Entry DOI: 10.7270/Q27S7MKF
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM183016 (US9150544, 50) Show SMILES CN(C)c1ncc(s1)S(=O)(=O)N[C@H]1CCN([C@H](Cc2cc3ccnc(N)c3cc2Cl)C(O)=O)C1=O |r| Show InChI InChI=1S/C21H23ClN6O5S2/c1-27(2)21-25-10-17(34-21)35(32,33)26-15-4-6-28(19(15)29)16(20(30)31)8-12-7-11-3-5-24-18(23)13(11)9-14(12)22/h3,5,7,9-10,15-16,26H,4,6,8H2,1-2H3,(H2,23,24)(H,30,31)/t15-,16+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The compounds according to the invention are tested in a range of concentrations (4.9 nM to 5 µM final) and deposited in a proportion of 25 µl per we...				US Patent US9150544 (2015) BindingDB Entry DOI: 10.7270/Q27S7MKF
					More data for this Ligand-Target Pair