BDBM183069 US9150544, 103

SMILES: COCCOc1cc2c(N)nccc2cc1C[C@@H](N1CC[C@H](NS(=O)(=O)c2cnc(s2)N(C)C)C1=O)C(O)=O

InChI Key: InChIKey=KEHAQUINLNOUGX-ZWKOTPCHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 183069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM183069 (US9150544, 103) Show SMILES COCCOc1cc2c(N)nccc2cc1C[C@@H](N1CC[C@H](NS(=O)(=O)c2cnc(s2)N(C)C)C1=O)C(O)=O |r| Show InChI InChI=1S/C24H30N6O7S2/c1-29(2)24-27-13-20(38-24)39(34,35)28-17-5-7-30(22(17)31)18(23(32)33)11-15-10-14-4-6-26-21(25)16(14)12-19(15)37-9-8-36-3/h4,6,10,12-13,17-18,28H,5,7-9,11H2,1-3H3,(H2,25,26)(H,32,33)/t17-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.0	n/a
Sanofi US Patent					Assay Description The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...				US Patent US9150544 (2015) BindingDB Entry DOI: 10.7270/Q27S7MKF
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM183069 (US9150544, 103) Show SMILES COCCOc1cc2c(N)nccc2cc1C[C@@H](N1CC[C@H](NS(=O)(=O)c2cnc(s2)N(C)C)C1=O)C(O)=O |r| Show InChI InChI=1S/C24H30N6O7S2/c1-29(2)24-27-13-20(38-24)39(34,35)28-17-5-7-30(22(17)31)18(23(32)33)11-15-10-14-4-6-26-21(25)16(14)12-19(15)37-9-8-36-3/h4,6,10,12-13,17-18,28H,5,7-9,11H2,1-3H3,(H2,25,26)(H,32,33)/t17-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The compounds according to the invention are tested in a range of concentrations (4.9 nM to 5 µM final) and deposited in a proportion of 25 µl per we...				US Patent US9150544 (2015) BindingDB Entry DOI: 10.7270/Q27S7MKF
					More data for this Ligand-Target Pair